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· Effective for Joints and Muscles: Penetrex is the whole-body therapy cream you’ve been waiting for; trusted by over 2 million sufferers; offers a different kind of comfort · The Penetrex Difference: Our proprietary blend of natural ingredients leverages the power of arnica, vitamin B6 and MSM to penetrate deeply for joint and muscle discomfort at the source · Premium Experience: Penetrex is a non-greasy, non-sticky, non-staining, paraben-free, cruelty-free and vegan soothing cream without the burn, freeze or strong odor of other products · See Why So Many People Trust Penetrex: Penetrex allows you to get back to doing the things you love · Directions: Apply to back, neck, knee, hand, foot, and more; Penetrex can be used on its own or with other therapies such as heating pads, ice packs, massagers and supplements; apply 3-4 times per day for 7-10 days, then apply as needed
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AndrewReviewed in the United States on July 7, 2015
I have suffered from RSIs for the past 5 years, and have been using Penetrex regularly for the past 2 years as part of my attempts to treat them. As anyone with RSIs know, these injuries are complex and poorly understood - it marks the beginning of an ongoing journey. In addition to my review of Penetrex, I will share some of my journey - maybe it will help someone else. I'll get right to the point: Does Penetrex have a positive effect, and is that effect worth the money? In my opinion, yes! However, it is no magic bullet. Penetrex is just one of many factors which can affect an injury, and while I have found it decently potent, it will not single-handidly right all wrongs in the RSI universe. If the only change you make in life is to start using Penetrex, it is unfair to poorly rate it if trouble still remains. I think perhaps the abundance of rave reviews could set some people up for disappointment; the rave reviews are completely deserved in my opinion, just remember the context of the person writing it. There are too many unpredictable factors to ensure that Penetrex will be a good fit for absolutely every person. But I would say that your odds are good, and for just $20, it is among the cheapest experiments in treatment you'll ever make. To those who complain about a lack of pain relief from Penetrex - I actually think the focus on pain relief is somewhat misplaced. I have always thought of Penetrex as a healing aid, and in that aspect I am very satisfied with its effectiveness. I have noticed some immediate relief upon application, but for me the difference has been in long-term recovery. You really do need to faithfully use it as directed to reap the maximum benefits. I don't need so much pain relief these days, as significantly less pain is being generated to begin with - something I am very grateful for. I don't know how exactly it works, but I'm aware that it does. For people with allergies and sensitive skin, I have read of some folks reacting negatively to this cream. Unfortunately, nothing works for everyone. For myself, I have generally troublesome allergies and struggle with psoriasis and eczema. I developed contact dermatitis from using wrist braces, and can't wear them anymore. But for all the grief my skin gives me, Penetrex has only had positive effects on me. When in doubt, do a patch test. I give this product 5 stars because, especially when you consider the cost of other treatments (and I'm not just talking about money), Penetrex delivers great bang for the buck. My experience with it leads me to believe that it is an inherently effective product backed by a reputable company. As I only seem to age in one direction - older - I anticipate being a customer of theirs for quite some time. Still struggling with RSIs though? Penetrex is a wonderful start, but most of us probably need more on top of this. Here's a distilled list of what I have found most effective over my years of struggle. It is these things which mean I am now healing over time instead of getting worse and worse. Maybe some of these suggestions will help you. I hope so! This is not medical advice, so please talk to your doctor before doing anything crazy. Best wishes. Alcohol - I could not believe the profound impact that even infrequent drinking had on my RSIs. It took me a long time to realize the correlation even existed. I've since quit drinking completely, and have improved significantly off this change alone. The takeaway - the occasional treat may still be punishing you chronically when it comes to what you eat/drink. Be mindful of what you put in your body! Trigger point therapy - overuse of muscles can cause them to permanently tense up, shortening the muscles and leading to irritation of the ligaments. Pressure is how you get the muscle fibers to release. I've gotten profound relief from this. There are some excellent products on amazon for self-massaging pressure points. It's been a real game changer for me. Exercising underused muscles - Releasing the tense overused muscles is just one side of the coin for me. I also need to exercise opposing muscle groups. For me, the best tool has been the flextend glove, which is available through their website. I was hesitant to buy it because it's expensive and their website is very ad jargony, but it gets to a point and you're willing to risk a big chunk of change just on the chance it helps. Well if part of your issue truly is muscle balance, the flextend helps a LOT. But like any exercise, you can hurt yourself using it. You don't need to go wild with the thing to get results! Workouts will sometimes cause me some irritation in the short term (cue Penetrex), but over the long term it has been very good for me. Frequent breaks from irritating activities: You really, really need to step away from your work frequently throughout the day. I use the pomodoro technique - I work for 25 minutes, then break for 5 (get up, move around, stretch). Every 2 hours, it's a 20 minute break. I use the handy program Focus Booster, which is free, to keep track of my time. This is also a documented technique for improving productivity, so if you have a cool boss, you might be able to sell them on introducing this at your workplace! Perfect ergonomics: If prices were bothering you before, you are really going to cry when it comes to this. As an example, I just spent over $600 on a new chair. That's the low end of the price spectrum you need to be looking in, if you work sitting down. And then there's the effort aspect - it takes time to habitually develop awareness of posture. But there's just no way around it - the best way to heal RSIs is to minimize the damage being done to begin with. Mechanical keyboard: If you do lots of typing, having a mechanical keyboard in a standard layout is superior to having a non-mechanical keyboard in an "ergonomic" layout. It's very difficult to find an "ergonomic" mechanical keyboard and they are very expensive. I am not sure if it's really worth it to go there. I just went with a standard layout and am very happy with it. The Cherry Red switches are the best for RSI sufferers, and you can additionally install red (2mm) or blue (4mm) rubber O rings on the underside of keys to reduce travel distance. Many suppliers will pre-install these for you, though Amazon sells key cap removal tools and the O rings for cheap, if you want to go DIY. I also recommend using a ten-keyless keyboard design unless you really use that numpad - and even then, you might consider a stand-alone numpad. The reduced travel distance between the keyboard and mouse adds up. Braces: While I used to swear by my wrist braces, I have grown to develop mixed feelings about them in the long run. I personally think they are best used as a short-term aid. They're best for when you're sleeping and during the most aggravating activities of the day, but be sure to give yourself significant "free time" if at all possible. If you're working with braces on, I think it's good to view them as a posture training tool more than anything else. Ideally, you should strive to reach a point where you can maintain good position without relying on the brace to enforce it. I hope some of this information proved useful to my fellow RSI sufferers! Good luck!!
AudryReviewed in the United States on March 21, 2025
Penetrex has been a game changer for my sore joints and muscles. I’ve used it on my back, neck, and even my hands after long workdays—and it always brings fast, soothing relief. It absorbs quickly, isn’t greasy, and has a light scent that fades fast. I really like that it’s made with quality ingredients like Arnica and MSM. The 2oz jar lasts longer than you’d think because a little goes a long way. Definitely a must-have in my medicine cabinet!
RayReviewed in the United States on August 15, 2024
Click to play video I have bought 10+ containers of it at this point. As someone with sensitive skin, it works perfectly fine and does not irritate. I appreciate that it barely has any smell. Easy to rub on. I sometimes use a glove when applying, but I try to avoid using gloves to be more environmentally friendly. It is not oily so it is not difficult to wash off your hands with simple soap and water anyways. Multiple members of my family use it. We used to use it very regularly when we had specific joint issues, but now it’s more just a use as needed basis for flare ups. We always like to have one handy. The 4 stars is because it’s a good product, but it’s nothing special and will not magically ease the pain overnight or anything. Just relieves a little and makes the healing process faster and more bearable.
Destiny JonesReviewed in the United States on March 20, 2025
This stuff works miracles frfr!!! My shoulder has been in pain for months. Aching every day and as soon as I rolled this product on my shoulder chile..... I was so busy going about my day that I didn't even realize my shoulder was no longer in pain until later on that day, and I was like OMG my shoulder doesn't hurt anymore!!! I was so overjoyed and amazed at the same time. So now anytime my muscles aching anywhere on my body, I just roll this product on and it works instantly. Will buy again!! Must TRY...10/10...I RECOMMEND!!!
Maya S.Reviewed in the United States on July 17, 2021
I have suffered from Runner's Knee (aka patellofemoral pain syndrome) for over 10 years. I don't have the pain all the time, but when it occurs it's usually only when walking or running. Typically the pain subsides on its own after a few hours of rest. But about a week ago I went on an 8-mile hike that completely messed up my right knee and I was out of commission for 4 days. I had no choice but to rest, ice, take ibuprofen, and compress during that time. I was desperate to alleviate the pain so I could resume normal activity. So I thought I would add Penetrex to my self-care routine. Penetrex is a cutaneous anti-inflammatory medication that is delivered through the skin. What appealed me to this specific brand was that it didn't appear to be pain masking like other brands. While heat and cold definitely dulls the sensation of pain, it can be dangerous in that it can give the illusion the problem is solved. So you may feel ready to resume activity and unknowingly make the injury worse. Penetrex doesn't do that. There is no heat, icy feeling, or numbness that occurs. I have tried both the cream and the roll-on and honestly I don't find much difference between the two in terms of efficacy. Typically, cutaneous (skin) medications are best delivered using a cream base. More often than not when you are prescribed a topical medication from your doctor or dermatologist, it is in a cream or ointment form. They don't evaporate as quickly and are more effective at delivering the medication. This roll-on is not a cream, but a clear serum-like liquid. It's definitely more convenient than the cream as you can just roll it on without getting it on your hands. It also dries much faster. Even after rubbing the cream into my skin for a while, the area remains somewhat tacky for about 15 to 20 minutes. The roll-on formula is dry within 2 to 3 minutes. But roll-ons are less hygenic than using a cream with a clean spatula (every time you roll all those dead skin cells start mixing with the ball and liquid), but the quick evaporation makes me wonder if the ingredients are able to penetrate the skin as well as the cream. I also find that the cream lasts longer as I can use less. But ultimately, does Penetrex really work? Or is it just an effective placebo? I can't really say for sure and that makes it hard for me to establish a fair rating (hence putting it somewhere in the middle). To be fair, I didn't see Runner's Knee as an issue this product claims to treat, so it could just be that it's not meant for that. I did feel like the pain did subside about a half hour after applying it, but the effects were temporary lasting only a few hours. I definitely had to apply it 3-4 times a day per the directions. Even so, it's hard to say if this cream is what actually relieved my pain as there were other variables to consider. I also iced my knee regularly, added compression, and kept off my feet during recovery. In all it took a full week for the pain to completely go away, and given the other methods I used it may have taken the same amount of time even without this cream. In conclusion, I'm not here to say that this cream doesn't work. It may work better for the conditions it actually claims to treat. But it certainly didn't perform any miracles on my knee. I want to be fair about this product though, and if I end up having some other type of pain I will certainly give both the cream and this roll-on another try. If it works, I'll update my review and the star rating.
MarinoReviewed in Mexico on May 25, 2022
El producto llego en el tiempo especificado y ha cumplido muy bien con el alivio en el dolor de las articulaciones. Aunque un poco caro, pero vale la pena.
Beza. GReviewed in the United Arab Emirates on December 16, 2023
Good
JoyReviewed in Australia on January 16, 2025
Very happy with this product, seems to work well and no smell
GrahamReviewed in Australia on September 3, 2024
Great works just great
KBReviewed in Australia on August 24, 2024
This cream is one of the better creams for relieving pain on the market. I have rebought this cream.